1,4-Dichlorobenzene

1,4-Dichlorobenzene

SCHEMBL28148441

COC=O.Clc1ccc(Cl)cc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.50
LMNA P02545 1/20 0.47
CYP2A6 P11509 1/20 0.47
HPGD P15428 1/20 0.41
ERN1 O75460 1/20 0.39
RAB9A P51151 2/20 0.39
NPC1 O15118 1/20 0.39
GAA P10253 1/20 0.39
HTT P42858 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CES2 O00748 2/20 0.38
CES1 P23141 2/20 0.38
ALDH1A1 P00352 1/20 0.38
CYP3A4 P08684 1/20 0.38
MAPK1 P28482 1/20 0.38
TDP1 Q9NUW8 1/20 0.37
IDO1 P14902 1/20 0.36
PKM P14618 1/20 0.36
MAOB P27338 2/20 0.36
MAOA P21397 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid Methyl Ester SCHEMBL28597388 0.84 CYP1A2 (0.62) LMNAERN1RAB9ANPC1GAA
Formic Acid Methyl Ester SCHEMBL28869151 0.81 CYP19A1 (0.39) HSD17B10HPGDRAB9ANPC1SMN1; SMN2
Formic Acid Methyl Ester SCHEMBL16044022 0.75 ALDH1A1 (0.36) CYP2A6ERN1RAB9ANPC1SMN1; SMN2
Formic Acid Methyl Ester SCHEMBL650 0.73
Formic Acid Methyl Ester SCHEMBL1332784 0.73
Formic Acid Methyl Ester SCHEMBL1330535 0.73
Formic Acid Methyl Ester SCHEMBL935999 0.73
Formic Acid Methyl Ester SCHEMBL28484615 0.72 CYP3A4 (0.45) HPGDGAASMN1; SMN2ALDH1A1CYP3A4
SCHEMBL3759283 0.72 HSD17B10 (0.46) HSD17B10LMNACYP2A6MAOBMAOA
SCHEMBL96633 0.72 HSD17B10 (0.46) HSD17B10LMNACYP2A6HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108929396-A A kind of rare-earth metal catalyst system and the method for preparing high-cis conjugated diene polymer 北京化工大学 2018-12-04 CN claimed
CN-106995517-B A kind of stereoregular styrene analog thermoplastic elastomer and preparation method thereof 北京化工大学 2019-06-18 CN disclosed
CN-108929396-A A kind of rare-earth metal catalyst system and the method for preparing high-cis conjugated diene polymer 北京化工大学 2018-12-04 CN disclosed
CN-108250327-A Siliceous functionalized polymeric with hydroxyl of a kind of end of the chain and preparation method thereof and branched polymer 北京化工大学 2018-07-06 CN disclosed
CN-108250371-A Bonding type polymer/silicon dioxide hybrid materials and preparation method thereof 北京化工大学 2018-07-06 CN disclosed
CN-106995517-A A kind of stereoregular styrene analog thermoplastic elastomer and preparation method thereof 北京化工大学 2017-08-01 CN disclosed