Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | FABP1 | P07148 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL15987298 | 0.89 | CA1 (0.50) | CA1CA2CA9KMT2AMEN1 | |
| SCHEMBL138895 | 0.89 | CA2 (0.58) | CA1CA2CA9KMT2AMEN1 | |
| Ether SCHEMBL387429 | 0.88 | CA1 (0.45) | CA1CA2CA9KMT2AMEN1 | |
| SCHEMBL28923781 | 0.87 | CA1 (0.52) | CA1CA2CA9KMT2AMEN1 | |
| Methylamine SCHEMBL7562548 | 0.87 | CA2 (0.58) | CA1CA2CA9KMT2AMEN1 | |
| Water SCHEMBL2134977 | 0.87 | CA1 (0.56) | CA1CA2CA9KMT2AMEN1 | |
| SCHEMBL17456405 | 0.87 | CA1 (0.56) | CA1CA2CA9KMT2AMEN1 | |
| Ammonia Solution, Strong SCHEMBL1115426 | 0.87 | CA1 (0.56) | CA1CA2CA9KMT2AMEN1 | |
| SCHEMBL17456525 | 0.87 | CA1 (0.56) | CA1CA2CA9KMT2AMEN1 | |
| SCHEMBL8058040 | 0.87 | CA1 (0.56) | CA1CA2CA9KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106867005-A | Sodium alginate with antibacterial and promotion wound healing function carries silver-colored graphene composite film and its application | 合肥工业大学 | 2017-06-20 | — | — | CN | claimed |
| CN-108854570-A | A kind of the fresh air system modified antibacterial water permeable membrane of graphene and preparation method | 济南开发区星火科学技术研究院 | 2018-11-23 | — | — | CN | disclosed |