Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | TTR | P02766 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.49 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | RXRB | P28702 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23152135 | 0.88 | MRGPRX4 (0.56) | MRGPRX4TSHRTTRPOLBCASP6 | |
| SCHEMBL8214320 | 0.86 | ALDH1A1 (0.55) | TSHRALDH1A1HPGDTP53 | |
| SCHEMBL6564724 | 0.85 | KDM4E (0.67) | MRGPRX4PTPN1TSHRPOLBDAPK1 | |
| SCHEMBL29262286 | 0.84 | MRGPRX4 (0.52) | MRGPRX4TSHRTTRPOLBCASP6 | |
| SCHEMBL20515885 | 0.83 | TSHR (0.53) | MRGPRX4TSHRPOLBCASP6GAA | |
| SCHEMBL1144405 | 0.83 | KDM4E (0.62) | MRGPRX4PTPN1TSHRTTRRAB9A | |
| SCHEMBL10780256 | 0.82 | PTPN1 (0.53) | MRGPRX4PTPN1TSHRTTRGAA | |
| SCHEMBL4328550 | 0.80 | ALDH1A1 (0.58) | MRGPRX4PTPN1TSHRTTRPOLB | |
| SCHEMBL1672695 | 0.80 | PLA2G4B (0.47) | MRGPRX4PTPN1TSHRSMN1; SMN2MEN1 | |
| SCHEMBL22570609 | 0.80 | PTPN1 (0.60) | MRGPRX4PTPN1DAPK1PIM3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107266667-A | Copolyester imide derived from aromatic dicarboxylic acid and aliphatic diol and the film being made from it | 杜邦帝人薄膜美国有限公司 | 2017-10-20 | — | — | CN | disclosed |
| CN-105612193-B | Copolyesterimides derived from aromatic dicarboxylic acids and aliphatic diols and films made therefrom | 杜邦帝人薄膜美国有限公司 | 2017-07-28 | — | — | CN | disclosed |