Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 7/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | UBE2N | P61088 | 1/20 | 0.40 |
| ▸ | COMT | P21964 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8944259 | 0.89 | L3MBTL1 (0.67) | L3MBTL1PTGDR2PTPN11HTR6CA12 | |
| SCHEMBL1906556 | 0.86 | L3MBTL1 (0.51) | L3MBTL1PTGDR2PTPN11HTR6CA12 | |
| SCHEMBL28523210 | 0.83 | L3MBTL1 (0.58) | L3MBTL1PTGDR2HTR6MEN1KMT2A | |
| SCHEMBL20292779 | 0.82 | L3MBTL1 (0.53) | L3MBTL1PTGDR2PTPN11HTR6LMNA | |
| SCHEMBL20292888 | 0.82 | L3MBTL1 (0.50) | L3MBTL1PTGDR2PTPN11HTR6LMNA | |
| SCHEMBL30280417 | 0.81 | L3MBTL1 (0.46) | L3MBTL1PTGDR2PTPN11HTR6CA1 | |
| SCHEMBL720190 | 0.81 | PTPN11 (0.49) | L3MBTL1PTPN11MAPK14HTR6LMNA | |
| SCHEMBL1666756 | 0.81 | L3MBTL1 (0.48) | L3MBTL1PTGDR2PTPN11HTR6MEN1 | |
| SCHEMBL16023214 | 0.80 | PTGDR2 (0.44) | L3MBTL1PTGDR2PTPN11HTR6COMT | |
| SCHEMBL20292764 | 0.80 | L3MBTL1 (0.53) | L3MBTL1PTGDR2PTPN11HTR6CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106854205-B | Inhibitors of influenza virus replication and methods of use and uses thereof | 广东东阳光药业有限公司 | 2019-07-09 | — | — | CN | disclosed |
| CN-109748915-A | Inhibitors of influenza viruses replication and its application method and purposes | 广东东阳光药业有限公司 | 2019-05-14 | — | — | CN | disclosed |
| CN-106854205-A | Inhibitors of influenza virus replication and methods of use and uses thereof | 广东东阳光药业有限公司 | 2017-06-16 | — | — | CN | disclosed |