Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.79 |
| ▸ | LMNA | P02545 | 2/20 | 0.79 |
| ▸ | MEN1 | O00255 | 1/20 | 0.79 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | JMJD1C | Q15652 | 1/20 | 0.37 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL125654 | 0.89 | KDM4E (1.00) | KDM4EKMT2ALMNAMEN1MGAM | |
| SCHEMBL30381290 | 0.89 | KDM4E (1.00) | KDM4EKMT2ALMNAMEN1MGAM | |
| SCHEMBL30505600 | 0.89 | KDM4E (1.00) | KDM4EKMT2ALMNAMEN1MGAM | |
| Fluoride SCHEMBL28821496 | 0.87 | KDM4E (0.96) | KDM4EKMT2ALMNAMEN1MGAM | |
| Hydrochloric Acid SCHEMBL5266713 | 0.87 | KDM4E (0.96) | KDM4EKMT2ALMNAMEN1MGAM | |
| SCHEMBL28821633 | 0.84 | KDM4E (0.90) | KDM4EKMT2ALMNAMEN1MGAM | |
| Methoxymethane SCHEMBL27938732 | 0.83 | KDM4E (0.87) | KDM4EKMT2ALMNAMEN1MGAM | |
| Benzamide SCHEMBL27821964 | 0.81 | KMT2A (0.77) | KDM4EKMT2ALMNAMEN1MGAM | |
| SCHEMBL30576393 | 0.80 | KDM4E (0.71) | KDM4EKMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL566150 | 0.80 | KDM4E (0.71) | KDM4EKMT2ALMNAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106817900-A | Novel naphthyridines and isoquinolin and its purposes as CDK8/19 inhibitor | 默克专利有限公司 | 2017-06-09 | — | — | CN | disclosed |