SCHEMBL28149240

SCHEMBL28149240

C=Cc1ccccc1C(CO)CCC

nearest known ligand 0.33

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
AOC3 Q16853 2/20 0.33
TAS1R3 Q7RTX0 1/20 0.32
TAS1R1 Q7RTX1 1/20 0.32
TSHR P16473 1/20 0.31
TP53 P04637 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
ALOX15 P16050 1/20 0.31
ALOX12 P18054 1/20 0.31
CYP2C19 P33261 1/20 0.31
HSD17B10 Q99714 1/20 0.31
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5033522 0.86 ALDH1A1 (0.35) ALDH1A1AOC3TAS1R3TAS1R1TSHR
SCHEMBL8578354 0.86 TSHR (0.36) ALDH1A1TSHR
SCHEMBL28503787 0.83 ALDH1A1 (0.33) ALDH1A1
SCHEMBL5974669 0.83 ALDH1A1 (0.33) ALDH1A1CYP2C19
SCHEMBL8741674 0.82 CYSLTR2 (0.40) ALDH1A1
SCHEMBL8576823 0.81 ALDH1A1 (0.36) ALDH1A1AOC3TAS1R3TAS1R1TSHR
SCHEMBL9351919 0.81 CYSLTR2 (0.42) ALDH1A1
Styrene SCHEMBL3148006 0.80 ALDH1A1 (0.42) ALDH1A1AOC3TAS1R3TAS1R1TSHR
SCHEMBL11406751 0.79 FFAR1 (0.42) ALDH1A1AOC3TAS1R3TAS1R1TSHR
SCHEMBL11295855 0.78 ALDH1A1 (0.40) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104024952-B Magnetic toner 佳能株式会社 2017-05-24 CN disclosed