Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 3/20 | 0.43 |
| ▸ | CDK4 | P11802 | 2/20 | 0.42 |
| ▸ | CCND1 | P24385 | 2/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.42 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.42 |
| ▸ | PRKCG | P05129 | 1/20 | 0.42 |
| ▸ | PRKCB | P05771 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29172842 | 0.82 | MAPT (0.69) | MAPTMEN1KMT2ACHEK1MAPK1 | |
| SCHEMBL3873502 | 0.81 | POLB (0.55) | TDP1POLBMAPTMEN1KMT2A | |
| SCHEMBL9550148 | 0.81 | MAPT (0.45) | TDP1MAPTMEN1KMT2ACHEK1 | |
| SCHEMBL3873238 | 0.78 | TDP1 (0.43) | TDP1POLBMAPTMEN1KMT2A | |
| SCHEMBL3881403 | 0.77 | UTS2R (0.46) | TDP1POLBMAPTMEN1KMT2A | |
| SCHEMBL27673109 | 0.76 | KDM4E (0.45) | TDP1POLBMAPTMEN1KMT2A | |
| SCHEMBL9644913 | 0.75 | MAPT (0.55) | TDP1POLBMAPTMEN1KMT2A | |
| SCHEMBL29459307 | 0.74 | KIF11 (0.58) | TDP1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL157116 | 0.74 | KIF11 (0.58) | TDP1MAPTMEN1KMT2AMAPK1 | |
| Water SCHEMBL1283772 | 0.73 | KIF11 (0.56) | TDP1MAPTMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107501330-A | Metal complex comprising azabenzimidazoles carbene ligands and its purposes in OLED | UDC 爱尔兰有限责任公司 | 2017-12-22 | — | — | CN | disclosed |
| CN-103732603-B | Metal complexes comprising azabenzimidazole carbene ligands and their use in OLEDs | UDC 爱尔兰有限责任公司 | 2017-05-31 | — | — | CN | disclosed |