Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | THRB | P10828 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.68 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.68 |
| ▸ | THPO | P40225 | 1/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.68 |
| ▸ | BLM | P54132 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 4/20 | 0.40 |
| ▸ | NOS1 | P29475 | 3/20 | 0.40 |
| ▸ | NOS3 | P29474 | 2/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cystine SCHEMBL28303896 | 0.94 | MAPT (0.60) | MAPTKDM4ETHRBALOX15NFKB1 | |
| Cystine SCHEMBL7049689 | 0.90 | MAPT (0.55) | MAPTKDM4ETHRBALOX15NFKB1 | |
| N-Monoacetylcystine SCHEMBL26134149 | 0.89 | MAPT (0.50) | MAPTKDM4ETHRBALOX15NFKB1 | |
| N-Monoacetylcystine SCHEMBL468826 | 0.88 | MAPT (0.48) | MAPTKDM4ETHRBALOX15NFKB1 | |
| N-Monoacetylcystine SCHEMBL29438781 | 0.88 | MAPT (0.48) | MAPTKDM4ETHRBALOX15NFKB1 | |
| N-Monoacetylcystine SCHEMBL20816351 | 0.88 | MAPT (0.48) | MAPTKDM4ETHRBALOX15NFKB1 | |
| N-Monoacetylcystine SCHEMBL111494 | 0.88 | MAPT (0.48) | MAPTKDM4ETHRBALOX15NFKB1 | |
| N-Monoacetylcystine SCHEMBL468824 | 0.88 | MAPT (0.48) | MAPTKDM4ETHRBALOX15NFKB1 | |
| Acetylcysteine SCHEMBL10351403 | 0.88 | MAPT (0.64) | MAPTKDM4ETHRBALOX15NFKB1 | |
| N-Monoacetylcystine SCHEMBL6368208 | 0.87 | MAPT (0.47) | MAPTKDM4ETHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106715707-A | Cell culture methods and media comprising n-acetylcysteine | 免疫医疗公司 | 2017-05-24 | — | — | CN | disclosed |