Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NOS2 | P35228 | 4/20 | 0.41 |
| ▸ | NOS1 | P29475 | 3/20 | 0.41 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GNPAT | O15228 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| N-Monoacetylcystine SCHEMBL6368194 | 1.00 | MAPT (0.47) | MAPTKDM4ETHRBALOX15NFKB1 | |
| N-Monoacetylcystine SCHEMBL20816351 | 0.98 | MAPT (0.48) | MAPTKDM4ETHRBALOX15NFKB1 | |
| N-Monoacetylcystine SCHEMBL29438781 | 0.98 | MAPT (0.48) | MAPTKDM4ETHRBALOX15NFKB1 | |
| N-Monoacetylcystine SCHEMBL468826 | 0.98 | MAPT (0.48) | MAPTKDM4ETHRBALOX15NFKB1 | |
| N-Monoacetylcystine SCHEMBL111494 | 0.98 | MAPT (0.48) | MAPTKDM4ETHRBALOX15NFKB1 | |
| N-Monoacetylcystine SCHEMBL468824 | 0.98 | MAPT (0.48) | MAPTKDM4ETHRBALOX15NFKB1 | |
| N-Monoacetylcystine SCHEMBL31253425 | 0.97 | MAPT (0.47) | MAPTKDM4ETHRBALOX15NFKB1 | |
| N-Monoacetylcystine SCHEMBL26134149 | 0.95 | MAPT (0.50) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL20839964 | 0.88 | MAPT (0.46) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL17749411 | 0.88 | NOS2 (0.44) | MAPTKDM4ETHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050175556-A1 | Skin Darkening (Sunless Tanning) Compositions Based on Enhancement of Melanin Synthesis by Tyrosinase Promoters | BIODERM RESEARCH (US) | 2005-08-11 | — | — | US | claimed |
| US-20050175556-A1 | Skin Darkening (Sunless Tanning) Compositions Based on Enhancement of Melanin Synthesis by Tyrosinase Promoters | BIODERM RESEARCH (US) | 2005-08-11 | — | — | US | disclosed |