Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15330740 | 0.78 | KDM4E (0.47) | KDM4EALDH1A1PKMPOLBMAPK1 | |
| SCHEMBL27726904 | 0.77 | MAPK1 (0.52) | KDM4EALDH1A1MAPK1SMN1; SMN2MEN1 | |
| SCHEMBL221665 | 0.76 | — | — | |
| SCHEMBL6755827 | 0.75 | KDM4E (0.57) | KDM4EALDH1A1PKMPOLBMAPK1 | |
| SCHEMBL2340816 | 0.72 | — | — | |
| SCHEMBL23483363 | 0.72 | KDM4E (0.46) | KDM4EALDH1A1PKMPOLBMAPK1 | |
| SCHEMBL11125720 | 0.72 | KDM4E (0.46) | KDM4EALDH1A1PKMPOLBMAPK1 | |
| SCHEMBL3555850 | 0.71 | — | — | |
| SCHEMBL309152 | 0.71 | — | — | |
| SCHEMBL22633135 | 0.71 | KDM4E (0.48) | KDM4EALDH1A1PKMPOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106661084-A | Macrocyclic broad spectrum antibiotics | 阿奇克斯制药公司 | 2017-05-10 | — | — | CN | disclosed |