Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2360816 | 0.78 | MAPK1 (0.51) | KDM4EGAAMAPK1KMOTSHR | |
| SCHEMBL9299670 | 0.78 | KDM4E (0.42) | KDM4EGAAALDH1A1PKMLMNA | |
| SCHEMBL28150960 | 0.78 | KDM4E (0.48) | KDM4EGAAMAPK1ALDH1A1PKM | |
| SCHEMBL2175235 | 0.76 | MAPK1 (0.68) | KDM4EGAAMAPK1ALDH1A1LMNA | |
| SCHEMBL25342529 | 0.74 | NLRP3 (0.47) | KDM4EMAPK1ALDH1A1KMOLMNA | |
| SCHEMBL16968020 | 0.73 | MAPK1 (0.46) | KDM4EMAPK1ALDH1A1KMOLMNA | |
| SCHEMBL1270152 | 0.73 | MAPK1 (0.42) | KDM4EMAPK1ALDH1A1KMOLMNA | |
| SCHEMBL14656717 | 0.73 | MAPK1 (0.42) | KDM4EMAPK1ALDH1A1KMOLMNA | |
| Butyric Acid SCHEMBL28289188 | 0.72 | MAPK1 (0.49) | KDM4EMAPK1ALDH1A1 | |
| SCHEMBL1155525 | 0.72 | IDO1 (0.43) | KDM4EMAPK1ALDH1A1KMOLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |