Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.43 |
| ▸ | PPARG | P37231 | 7/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL692135 | 0.90 | CYP1A2 (0.46) | PPARAPPARGCYP1A2CYP2C19MEN1 | |
| Phosphine SCHEMBL27522539 | 0.88 | CYP1A2 (0.45) | PPARAPPARGCYP1A2CYP2C19MEN1 | |
| SCHEMBL28107544 | 0.88 | CYP1A2 (0.45) | PPARAPPARGCYP1A2CYP2C19MEN1 | |
| Ammonia Solution, Strong SCHEMBL27869910 | 0.88 | CYP1A2 (0.45) | PPARAPPARGCYP1A2CYP2C19MEN1 | |
| SCHEMBL28219394 | 0.88 | CYP1A2 (0.45) | PPARAPPARGCYP1A2CYP2C19MEN1 | |
| Water SCHEMBL28856009 | 0.88 | CYP1A2 (0.45) | PPARAPPARGCYP1A2CYP2C19MEN1 | |
| Dimethylamine SCHEMBL27533034 | 0.87 | PPARA (0.42) | PPARAPPARGCYP1A2CYP2C19MEN1 | |
| Naphthalene SCHEMBL28287447 | 0.85 | CYP1A2 (0.42) | PPARAPPARGCYP1A2CYP2C19MEN1 | |
| SCHEMBL28223797 | 0.81 | ALOX15 (0.67) | PPARGMEN1MAPTKMT2AALOX15 | |
| SCHEMBL27352386 | 0.79 | TSHR (0.51) | PPARAPPARGCYP1A2MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106818747-A | A kind of coated slow-release plant growth regulator and preparation method and application | 东莞市联洲知识产权运营管理有限公司 | 2017-06-13 | — | — | CN | disclosed |