Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.71 |
| ▸ | F3 | P13726 | 1/20 | 0.71 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.71 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.71 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.71 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.71 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.71 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.71 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.71 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.49 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Niacin SCHEMBL9679976 | 0.85 | ALDH1A1 (0.70) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL19978192 | 0.84 | — | — | |
| Niacinamide SCHEMBL29624874 | 0.84 | — | — | |
| Niacinamide SCHEMBL2926 | 0.84 | — | — | |
| Niacinamide SCHEMBL460466 | 0.84 | F7 (1.00) | F7F3SARM1SIRT2SIRT6 | |
| Benzamide SCHEMBL29283553 | 0.83 | POLB (0.59) | F7F3SARM1SIRT2SIRT6 | |
| Benzamide SCHEMBL5106831 | 0.83 | POLB (0.59) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL25366418 | 0.82 | — | — | |
| Niacinamide SCHEMBL11410594 | 0.82 | F7 (0.96) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL9064246 | 0.82 | F7 (0.96) | F7F3SARM1SIRT2SIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106699732-A | Preparation of pyrazole nicotinamide compound and application thereof as bactericide | 安徽农业大学 | 2017-05-24 | — | — | CN | claimed |
| CN-108383791-A | A kind of amides compound and its preparation method and application | 上海泰禾国际贸易有限公司 | 2018-08-10 | — | — | CN | disclosed |
| CN-106699732-A | Preparation of pyrazole nicotinamide compound and application thereof as bactericide | 安徽农业大学 | 2017-05-24 | — | — | CN | disclosed |
| CN-106699732-A | Preparation of pyrazole nicotinamide compound and application thereof as bactericide | 安徽农业大学 | 2017-05-24 | — | — | CN | disclosed |
| CN-106699732-A | Preparation of pyrazole nicotinamide compound and application thereof as bactericide | 安徽农业大学 | 2017-05-24 | — | — | CN | disclosed |