Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PREP | P48147 | 2/20 | 0.31 |
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26206910 | 0.81 | TDP1 (0.38) | TDP1PREPDPP4MEN1KMT2A | |
| SCHEMBL19883625 | 0.76 | TDP1 (0.46) | TDP1PREPMEN1KMT2ACYP2C9 | |
| SCHEMBL16076329 | 0.76 | TDP1 (0.46) | TDP1PREPMEN1KMT2ACYP2C9 | |
| SCHEMBL18943176 | 0.76 | TDP1 (0.46) | TDP1PREPMEN1KMT2ACYP2C9 | |
| SCHEMBL15430116 | 0.76 | TDP1 (0.46) | TDP1PREPMEN1KMT2ACYP2C9 | |
| SCHEMBL18829248 | 0.76 | TDP1 (0.46) | TDP1PREPMEN1KMT2ACYP2C9 | |
| SCHEMBL18177041 | 0.76 | TDP1 (0.46) | TDP1PREPMEN1KMT2ACYP2C9 | |
| SCHEMBL18389492 | 0.74 | TDP1 (0.34) | TDP1ALDH1A1PREPMEN1KMT2A | |
| SCHEMBL26999790 | 0.74 | TDP1 (0.34) | TDP1ALDH1A1PREPMEN1KMT2A | |
| SCHEMBL21173306 | 0.72 | PREP (0.39) | TDP1PREPCYP2C9CYP2D6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106928127-B | Substituted piperidine amide derivative, preparation method and pharmaceutical application thereof | 四川海思科制药有限公司 | 2021-07-16 | — | — | CN | disclosed |
| CN-106928127-A | Substituted piperidine class amide derivatives and preparation method thereof and application pharmaceutically | 四川海思科制药有限公司 | 2017-07-07 | — | — | CN | disclosed |