Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 5/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | CD74 | P04233 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | SCN4A | P35499 | 4/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1814558 | 0.74 | NOTUM (0.58) | NOTUMPOLBPTPN11RAB9AMAPK1 | |
| SCHEMBL1811890 | 0.73 | NOTUM (0.61) | NOTUM | |
| SCHEMBL28242340 | 0.72 | NOTUM (0.40) | NOTUM | |
| SCHEMBL5569809 | 0.70 | PDPK1 (0.61) | NOTUMPOLBPTPN11NPC1RAB9A | |
| SCHEMBL14896097 | 0.68 | NOTUM (0.58) | NOTUMPOLBPTPN11NPC1RAB9A | |
| SCHEMBL17279817 | 0.68 | POLB (0.77) | NOTUMPOLBPTPN11NPC1RAB9A | |
| SCHEMBL12947153 | 0.68 | IDO1 (0.42) | IDO1 | |
| SCHEMBL15327070 | 0.66 | NOTUM (1.00) | NOTUMPOLBPTPN11NPC1RAB9A | |
| SCHEMBL12509626 | 0.66 | SMN1; SMN2 (0.38) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14823831 | 0.66 | HSD17B3 (0.41) | POLBNPC1RAB9AMIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105061313-B | Androgen receptor modulating compounds | 奥赖恩公司 | 2017-07-18 | — | — | CN | disclosed |