SCHEMBL1814558

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21145379	0.79	MAPT (0.50)	NOTUMMEN1KMT2AHTTMITF
	SCHEMBL22353104	0.79	AR (0.46)	MEN1KMT2AHTTMAPTAR
	SCHEMBL4554080	0.77	NOTUM (0.61)	NOTUMMEN1KMT2AHTTMITF
	SCHEMBL1813050	0.76	MAPT (0.47)	NOTUMMEN1KMT2AHTTMITF
	SCHEMBL12076512	0.76	NPC1 (0.50)	NOTUMMEN1KMT2AHTTMITF
	SCHEMBL29074284	0.74	CRHBP (0.49)	MEN1KMT2AHTTARSIRT6
	SCHEMBL11624085	0.74	KDR (0.46)	MEN1KMT2AARSIRT6CYP3A4
	SCHEMBL28153458	0.74	NOTUM (0.61)	NOTUMSMN1; SMN2RAB9AMAPK1POLB
	SCHEMBL1807875	0.73	VCAM1 (0.50)	NOTUMMEN1KMT2AHTTMITF
	SCHEMBL28242342	0.73	AR (0.46)	NOTUMMEN1KMT2AHTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.