Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 4/20 | 0.38 |
| ▸ | CES1 | P23141 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 2/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | PAM | P19021 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 4/20 | 0.35 |
| ▸ | PPARD | Q03181 | 4/20 | 0.35 |
| ▸ | PPARA | Q07869 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28154103 | 0.98 | KMT2A (0.43) | KMT2AMAPTCES2CES1HAO1 | |
| SCHEMBL27981152 | 0.98 | KMT2A (0.43) | KMT2AMAPTCES2CES1HAO1 | |
| SCHEMBL27960379 | 0.98 | KMT2A (0.43) | KMT2AMAPTCES2CES1HAO1 | |
| SCHEMBL27960370 | 0.95 | CES1 (0.35) | KMT2AMAPTCES2CES1L3MBTL1 | |
| SCHEMBL28155023 | 0.76 | CYP3A4 (0.39) | L3MBTL1TDP1TSHRALDH1A1HSD17B10 | |
| SCHEMBL25180042 | 0.74 | NAAA (0.47) | KMT2AMAPTCES2CES1L3MBTL1 | |
| SCHEMBL12443034 | 0.74 | NAAA (0.49) | MAPTCES2CES1NAAAPAM | |
| SCHEMBL18597085 | 0.74 | NAAA (0.49) | MAPTCES2CES1NAAAPAM | |
| SCHEMBL28155012 | 0.71 | CYP19A1 (0.30) | — | |
| SCHEMBL8737871 | 0.70 | CYP19A1 (0.37) | KMT2AMEN1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104053682-B | For the high activity catalyst component and its application method of olefinic polymerization | 格雷斯公司 | 2017-05-31 | — | — | CN | claimed |
| CN-103619475-B | Emulsion method for improved big spherical polypropylene catalyst | 格雷斯公司 | 2017-08-04 | — | — | CN | disclosed |
| CN-104053682-B | For the high activity catalyst component and its application method of olefinic polymerization | 格雷斯公司 | 2017-05-31 | — | — | CN | disclosed |