Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL28154338

Cc1ccc(C(=O)C(=O)c2ccccc2)cc1C.N

nearest known ligand 0.96

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CES2 O00748 11/20 0.96
CES1 P23141 10/20 0.96
ALDH1A1 P00352 2/20 0.56
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53
KMT2A Q03164 2/20 0.53
MAPT P10636 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
MITF O75030 1/20 0.51
LMNA P02545 1/20 0.51
POLB P06746 1/20 0.51
HTT P42858 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
TSHR P16473 1/20 0.47
MEN1 O00255 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2156354 0.98 CES2 (1.00) CES2CES1ALDH1A1NPC1RAB9A
SCHEMBL9420251 0.87 CES2 (0.79) CES2CES1ALDH1A1NPC1RAB9A
Benzoic Acid SCHEMBL29130879 0.82 CES2 (0.71) CES2CES1ALDH1A1NPC1RAB9A
SCHEMBL166495 0.82 SMN1; SMN2 (0.71) CES2CES1ALDH1A1NPC1RAB9A
SCHEMBL10007010 0.82 SMN1; SMN2 (0.71) CES2CES1ALDH1A1NPC1RAB9A
SCHEMBL10582008 0.81 CES2 (0.70) CES2CES1ALDH1A1NPC1RAB9A
SCHEMBL9305463 0.79 CES2 (0.68) CES2CES1ALDH1A1NPC1RAB9A
SCHEMBL31221137 0.79 CES2 (0.67) CES2CES1ALDH1A1NPC1RAB9A
SCHEMBL13236538 0.78 TDP1 (0.69) CES2CES1ALDH1A1NPC1RAB9A
SCHEMBL1195835 0.78 CES2 (1.00) CES2CES1ALDH1A1RAB9ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107109190-A The manufacture method of electronic device sealant and electronic device 积水化学工业株式会社 2017-08-29 CN disclosed