Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.48 |
| ▸ | SPR | P35270 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 3/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28154393 | 0.99 | HSD11B1 (0.49) | HSD11B1SPRALDH1A1KDM4EHSD17B10 | |
| SCHEMBL28154397 | 0.96 | HSD11B1 (0.46) | HSD11B1SPRALDH1A1KDM4EHSD17B10 | |
| SCHEMBL28154390 | 0.96 | HSD11B1 (0.48) | HSD11B1SPRALDH1A1POLBACACB | |
| SCHEMBL28154386 | 0.95 | HSD11B1 (0.47) | HSD11B1SPRALDH1A1KDM4EHSD17B10 | |
| SCHEMBL28155324 | 0.91 | ACACB (0.47) | HSD11B1SPRALDH1A1KDM4EHSD17B10 | |
| SCHEMBL28155321 | 0.85 | HSD11B1 (0.49) | HSD11B1SPRALDH1A1ACACBCYP11B2 | |
| SCHEMBL15529770 | 0.85 | NAMPT (0.55) | NAMPT | |
| SCHEMBL15528927 | 0.84 | NAMPT (0.56) | NAMPT | |
| SCHEMBL15529097 | 0.84 | HSD11B1 (0.50) | HSD11B1SPRPOLBACACBCYP11B2 | |
| SCHEMBL28155323 | 0.84 | HSD11B1 (0.46) | HSD11B1SPRALDH1A1POLBACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104684906-B | Nampt inhibitor | 艾伯维公司 | 2017-06-09 | — | — | CN | claimed |
| CN-104684906-B | Nampt inhibitor | 艾伯维公司 | 2017-06-09 | — | — | CN | disclosed |