Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 12/20 | 0.41 |
| ▸ | IDO1 | P14902 | 8/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | PAK4 | O96013 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL101638 | 0.68 | — | — | |
| SCHEMBL3204384 | 0.67 | METAP2 (0.41) | METAP2IDO1KEAP1METAP1NOTUM | |
| SCHEMBL5838655 | 0.66 | — | — | |
| SCHEMBL22206279 | 0.66 | — | — | |
| SCHEMBL6260959 | 0.66 | — | — | |
| SCHEMBL31058751 | 0.65 | — | — | |
| SCHEMBL31058753 | 0.65 | — | — | |
| SCHEMBL12075530 | 0.65 | MEN1 (0.36) | — | |
| SCHEMBL16862629 | 0.64 | — | — | |
| SCHEMBL12598648 | 0.64 | CCR1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106883424-B | Energetic alkaline earth metal-organic frame and preparation method thereof | 中国工程物理研究院化工材料研究所 | 2019-12-24 | — | — | CN | disclosed |
| CN-106883423-B | Energetic alkali metal-organic frameworks and methods of making same | 中国工程物理研究院化工材料研究所 | 2019-12-24 | — | — | CN | disclosed |
| CN-106905539-B | Metal-organic framework containing energy and preparation method thereof | 中国工程物理研究院化工材料研究所 | 2019-11-05 | — | — | CN | disclosed |
| CN-106905539-A | Metal organic frame containing energy and preparation method thereof | 中国工程物理研究院化工材料研究所 | 2017-06-30 | — | — | CN | disclosed |
| CN-106883423-A | Alkali metal organic frame containing energy and preparation method thereof | 中国工程物理研究院化工材料研究所 | 2017-06-23 | — | — | CN | disclosed |
| CN-106883424-A | The alkaline-earth metal containing energy has machine frame and preparation method thereof | 中国工程物理研究院化工材料研究所 | 2017-06-23 | — | — | CN | disclosed |