Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | HMGCR | P04035 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15698069 | 0.79 | HSP90AB1 (0.42) | GAAKMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL20142067 | 0.77 | GAA (0.55) | GAAKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL1020355 | 0.75 | GAA (0.53) | GAAKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL27757665 | 0.73 | HMGCR (0.51) | KMT2AMEN1ALDH1A1HPGDTSHR | |
| SCHEMBL28358548 | 0.72 | HSP90AB1 (0.48) | KMT2AMEN1ALDH1A1HPGDTSHR | |
| SCHEMBL7193425 | 0.72 | CYP3A4 (0.44) | GAAKMT2AMEN1ALDH1A1HSD17B10 | |
| SCHEMBL26519532 | 0.72 | TSHR (0.48) | GAAKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL22055395 | 0.72 | KDM4E (0.42) | GAAKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL1023702 | 0.71 | HSP90AB1 (0.39) | GAAKMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL22614748 | 0.71 | HSP90AB1 (0.47) | GAAKMT2AMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104254534-B | Modulators of HEC1 activity and methods thereof | 泰纬生命科技股份有限公司 | 2017-07-14 | — | — | CN | disclosed |