Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | KDR | P35968 | 2/20 | 0.55 |
| ▸ | SNCA | P37840 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28888670 | 0.92 | SNCA (0.56) | KDM4EKDRSNCAKMT2ATP53 | |
| SCHEMBL28396655 | 0.89 | CYP1A2 (0.58) | KDM4EKDRSNCAKMT2ATP53 | |
| SCHEMBL28392613 | 0.89 | SNCA (0.58) | KDM4ESNCAKMT2AADORA3MEN1 | |
| SCHEMBL28155563 | 0.86 | KDM4E (0.60) | KDM4ESNCAKMT2ATP53APP | |
| SCHEMBL28400033 | 0.85 | KDM4E (0.60) | KDM4EKDRSNCAKMT2ATP53 | |
| SCHEMBL28155562 | 0.83 | KDM4E (0.56) | KDM4ESNCAKMT2ATP53APP | |
| SCHEMBL28400677 | 0.83 | KDM4E (0.56) | KDM4EKMT2ATP53APPHDAC6 | |
| SCHEMBL28434027 | 0.79 | KDR (0.63) | KDM4EKDRKMT2ATP53HDAC6 | |
| SCHEMBL28891850 | 0.79 | KDR (0.63) | KDM4EKDRKMT2ATP53HDAC6 | |
| SCHEMBL23360257 | 0.78 | KMT2A (0.74) | KDM4EKDRKMT2ATP53HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106938985-B | 5-site alkenylated 8-acylaminoquinoline compound and one-pot preparation method thereof | 湖南大学 | 2020-05-05 | — | — | CN | disclosed |
| CN-106938985-A | A kind of 5 amide groups quinolines of alkenyl 8 and its one-pot preparation thereof | 湖南大学 | 2017-07-11 | — | — | CN | disclosed |