Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28396770 | 0.87 | KDM4E (0.50) | KDM4ELMNAHTTATG4BALDH1A1 | |
| SCHEMBL28155563 | 0.87 | KDM4E (0.60) | KDM4EADORA3APPKMT2ANPC1 | |
| SCHEMBL28155562 | 0.84 | KDM4E (0.56) | KDM4EAPPKMT2ANPC1RAB9A | |
| SCHEMBL28154676 | 0.83 | KDM4E (0.59) | KDM4EADORA3APPKMT2ANPC1 | |
| SCHEMBL28400033 | 0.79 | KDM4E (0.60) | KDM4EAPPKMT2ANPC1RAB9A | |
| SCHEMBL28888670 | 0.79 | SNCA (0.56) | KDM4EAPPKMT2ANPC1RAB9A | |
| SCHEMBL28392613 | 0.78 | SNCA (0.58) | KDM4EADORA3KMT2ANPC1RAB9A | |
| SCHEMBL28160383 | 0.78 | CKS1B (0.60) | KMT2ATP53 | |
| SCHEMBL28393701 | 0.78 | KDM4E (0.54) | KDM4EAPPKMT2ARAB9ALMNA | |
| SCHEMBL28396655 | 0.76 | CYP1A2 (0.58) | KDM4EKMT2ANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106938985-B | 5-site alkenylated 8-acylaminoquinoline compound and one-pot preparation method thereof | 湖南大学 | 2020-05-05 | — | — | CN | disclosed |