SCHEMBL28155137

SCHEMBL28155137

C[C](C)CN1CCO[C@@H](C=O)C1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PDK1 Q15118 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14941197 0.80 DRD3 (0.38)
SCHEMBL14940773 0.77 KDM4E (0.41)
SCHEMBL28766847 0.75 GLB1 (0.37)
SCHEMBL28155217 0.75 PDK1 (0.35) PDK1
SCHEMBL28156023 0.75 PDK1 (0.35) PDK1
SCHEMBL28194719 0.74 DRD4 (0.35) PDK1
SCHEMBL28853353 0.74 DRD3 (0.33) PDK1
SCHEMBL14940873 0.73 MEN1 (0.33)
SCHEMBL29257701 0.71 SMN1; SMN2 (0.44) PDK1
SCHEMBL27687247 0.71 PDK1 (0.46) PDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104945395-B Dihydropyrimidines and its application in medicine 广东东阳光药业有限公司 2018-01-23 CN disclosed
CN-107485612-A Imidazopyridine and application thereof 尼奥迈德研究所 2017-12-19 CN disclosed
CN-105246888-B Imidazopyridine compounds and uses thereof 尼奥迈德研究所 2017-09-05 CN disclosed