Threonine

Threonine

SCHEMBL28155188

CC(O)C(N)C(=O)O.c1c[nH]cn1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.46
FKBP5 Q13451 1/20 0.46
SLC7A5 Q01650 2/20 0.39
SLC1A3 P43003 1/20 0.31
SLC1A2 P43004 1/20 0.31
SLC1A1 P43005 1/20 0.31
CYP3A4 P08684 1/20 0.30
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Threonine SCHEMBL28637557 1.00 ALDH1A1 (0.46) ALDH1A1FKBP5SLC7A5SLC1A3SLC1A2
Valine SCHEMBL645699 0.89 SLC7A5 (0.54) ALDH1A1FKBP5SLC7A5SLC1A3SLC1A2
Valine SCHEMBL645697 0.89 SLC7A5 (0.54) ALDH1A1FKBP5SLC7A5SLC1A3SLC1A2
Valine SCHEMBL7279040 0.89 SLC7A5 (0.54) ALDH1A1FKBP5SLC7A5SLC1A3SLC1A2
Alanine SCHEMBL8532378 0.87 ALDH1A1 (0.52) ALDH1A1FKBP5SLC7A5CYP3A4
Alanine SCHEMBL8532370 0.87 ALDH1A1 (0.52) ALDH1A1FKBP5SLC7A5CYP3A4
Lactic Acid SCHEMBL1331765 0.85 ALDH1A1 (0.54) ALDH1A1FKBP5TP53
Isoleucine SCHEMBL28155191 0.85 ALDH1A1 (0.42) ALDH1A1FKBP5SLC7A5
Imidazole SCHEMBL2158081 0.83 ALDH1A1 (0.56) ALDH1A1FKBP5TP53
Imidazole SCHEMBL16859470 0.79 ALDH1A1 (0.52) ALDH1A1FKBP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113416472-B Water-based bi-component epoxy primer for racing helmet and preparation method thereof 雅图高新材料股份有限公司 2022-03-18 CN claimed
CN-113416472-A Water-based bi-component epoxy primer for racing helmet and preparation method thereof 雅图高新材料股份有限公司 2021-09-21 CN claimed
CN-113416472-B Water-based bi-component epoxy primer for racing helmet and preparation method thereof 雅图高新材料股份有限公司 2022-03-18 CN disclosed
CN-113416472-A Water-based bi-component epoxy primer for racing helmet and preparation method thereof 雅图高新材料股份有限公司 2021-09-21 CN disclosed
CN-106966988-A A kind of method of use microwave radiation synthesizing amino acid imidazole salts in aqueous 上海应用技术大学 2017-07-21 CN disclosed