Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC4 | O15439 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3041677 | 0.98 | ABCC4 (0.46) | ABCC4MAPTALDH1A1LMNAL3MBTL1 | |
| SCHEMBL6120452 | 0.95 | ABCC4 (0.45) | ABCC4MAPTALDH1A1LMNAL3MBTL1 | |
| SCHEMBL3968169 | 0.95 | ABCC4 (0.45) | ABCC4MAPTALDH1A1LMNAL3MBTL1 | |
| SCHEMBL12614147 | 0.91 | MAPT (0.52) | ABCC4MAPTALDH1A1LMNAL3MBTL1 | |
| SCHEMBL4013371 | 0.76 | MAPT (0.48) | ABCC4MAPTALDH1A1LMNAL3MBTL1 | |
| SCHEMBL5745232 | 0.76 | HIF1A (0.43) | MAPTTSHRACLY | |
| SCHEMBL5950908 | 0.76 | MAPT (0.48) | ABCC4MAPTALDH1A1LMNAL3MBTL1 | |
| SCHEMBL4539892 | 0.76 | ABCC4 (0.39) | ABCC4MAPTALDH1A1LMNAL3MBTL1 | |
| Zinc Ion SCHEMBL6120455 | 0.76 | ABCC4 (0.39) | ABCC4MAPTALDH1A1LMNAL3MBTL1 | |
| SCHEMBL5998393 | 0.74 | MAPT (0.42) | ABCC4MAPTALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106749032-B | A kind of preparation method of novel rosuvastain calcium intermediate | 浙江永太药业有限公司 | 2019-07-16 | — | — | CN | disclosed |
| CN-106749032-A | A kind of preparation method of novel rosuvastain calcium intermediate | 浙江永太药业有限公司 | 2017-05-31 | — | — | CN | disclosed |