SCHEMBL3041677

SCHEMBL3041677

C=CCCCC(O)(O)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ABCC4 O15439 1/20 0.46
MAPT P10636 1/20 0.46
ALDH1A1 P00352 5/20 0.36
LMNA P02545 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
TSHR P16473 3/20 0.35
ACLY P53396 1/20 0.33
LPAR2 Q9HBW0 1/20 0.32
LPAR3 Q9UBY5 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3968169 0.98 ABCC4 (0.45) ABCC4MAPTALDH1A1LMNAL3MBTL1
SCHEMBL28157601 0.98 ABCC4 (0.45) ABCC4MAPTALDH1A1LMNAL3MBTL1
SCHEMBL6120452 0.98 ABCC4 (0.45) ABCC4MAPTALDH1A1LMNAL3MBTL1
SCHEMBL12614147 0.94 MAPT (0.52) ABCC4MAPTALDH1A1LMNAL3MBTL1
SCHEMBL5745232 0.78 HIF1A (0.43) MAPTTSHRACLY
SCHEMBL5950908 0.78 MAPT (0.48) ABCC4MAPTALDH1A1LMNAL3MBTL1
SCHEMBL4013371 0.78 MAPT (0.48) ABCC4MAPTALDH1A1LMNAL3MBTL1
SCHEMBL4539892 0.77 ABCC4 (0.39) ABCC4MAPTALDH1A1LMNAL3MBTL1
Zinc Ion SCHEMBL6120455 0.77 ABCC4 (0.39) ABCC4MAPTALDH1A1LMNAL3MBTL1
SCHEMBL5998393 0.76 MAPT (0.42) ABCC4MAPTALDH1A1LMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9296702-B2 Rosuvastatin enantiomer compounds SCALLEN, MICHAEL 2016-03-29 US claimed
WO-2012063115-A2 PROCESS FOR THE PREPARATION OF ROSUVASTATIN CALCIUM VIA NOVEL AMINE INTERMEDIATE JUBILANT LIFE SCIENCES LTD. (IN) 2012-05-18 WO claimed
WO-2010030201-A2 STABLE ORAL PHARMACEUTICAL COMPOSITION CONTAINING A PHARMACEUTICALLY ACCEPTABLE SALT OF [(E)-7-[4-(4-FLUOROPHENYL)-6-ISOPROPYL-2- [METHYL(METHYLSULFONYL)AMINO]PYRIMIDINE-5-YL] (3R, 5S) - 3,5 DIHYDROXYHEPT-6- ENOIC ACID ZAKLADY FARMACEUTYCZNE POLPHARMA SA (PL) 2010-03-18 WO claimed
EP-1223918-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING A HMG COA REDUCTASE INHIBITOR AstraZeneca AB (SE) 2002-07-24 EP claimed
WO-2001054668-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING A HMG REDUCTASE INHIBITOR ASTRAZENECA AB (SE) 2001-08-02 WO claimed
EP-0300249-B1 7-[1H-pyrrol-3-yl]-substituted 3,5-dihydroxy-heptane acids, their corresponding delta-lactones and salts, processes for their manufacture, their use as medicines, pharmaceutical preparations and intermediates HOECHST AKTIENGESELLSCHAFT (DE) 1993-02-03 EP claimed
EP-0300249-A1 7-[1H-pyrrol-3-yl]-substituted 3,5-dihydroxy-heptane acids, their corresponding delta-lactones and salts, processes for their manufacture, their use as medicines, pharmaceutical preparations and intermediates HOECHST AKTIENGESELLSCHAFT (DE) 1989-01-25 EP claimed
JP-10067744-A None JP disclosed
WO-2025090648-A1 METHODS AND COMPOSITIONS FOR INHIBITING METASTASIS OF SOLID TUMORS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-05-01 WO disclosed
CN-118772052-A Medical intermediate and preparation method thereof 湖南九维生物医药有限公司 2024-10-15 CN disclosed
US-11466252-B2 Expansion and differentiation of inner ear supporting cells and methods of use thereof MASSACHUSETTS EYE AND EAR INFIRMARY (US) 2022-10-11 US disclosed
EP-3833335-A1 PHARMACEUTICAL COMPOSITION COMPRISING HMG-COA REDUCTASE INHIBITORS AND FENOFIBRATE Intas Pharmaceuticals Ltd. (IN) 2021-06-16 EP disclosed
WO-2021019493-A1 PHARMACEUTICAL COMPOSITION COMPRISING HMG-COA REDUCTASE INHIBITORS AND FENOFIBRATE INTAS PHARMACEUTICALS LTD. (IN) 2021-02-04 WO disclosed
JP-H1067744-A 6-(HYDROXYMETHYL-ETHYL) PYRIDINE BAYER AG 1998-03-10 JP disclosed
EP-0617000-A2 4-Fluorobiphenyl derivatives FUJIREBIO Inc. (JP) 1994-09-28 EP disclosed
EP-0361273-B1 7-Substituted derivatives of 3,5-dihydroxyhept-6-inoic acid, process for their preparation, their use as medicaments, and intermediates HOECHST AG (DE) 1994-03-23 EP disclosed
EP-0300249-B1 7-[1H-pyrrol-3-yl]-substituted 3,5-dihydroxy-heptane acids, their corresponding delta-lactones and salts, processes for their manufacture, their use as medicines, pharmaceutical preparations and intermediates HOECHST AKTIENGESELLSCHAFT (DE) 1993-02-03 EP disclosed
US-5055484-A Anticholesterol and antilipemic agent HOECHST AKTIENGESELLSCHAFT (DE) 1991-10-08 US disclosed
EP-0361273-A2 7-Substituted derivatives of 3,5-dihydroxyhept-6-inoic acid, process for their preparation, their use as medicaments, and intermediates HOECHST AKTIENGESELLSCHAFT (DE) 1990-04-04 EP disclosed
EP-0244364-A2 Preparation of olefinic compounds SANDOZ AG (CH) 1987-11-04 EP disclosed