Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28153950 | 0.82 | DRD3 (0.37) | DRD3 | |
| SCHEMBL21341346 | 0.76 | — | — | |
| SCHEMBL18975892 | 0.70 | — | — | |
| SCHEMBL24943290 | 0.67 | DRD3 (0.32) | DRD3 | |
| SCHEMBL18975587 | 0.67 | ALDH1A1 (0.36) | DRD3 | |
| SCHEMBL18975737 | 0.67 | DRD3 (0.33) | DRD3 | |
| SCHEMBL28176949 | 0.66 | — | — | |
| SCHEMBL9921782 | 0.66 | — | — | |
| SCHEMBL23343604 | 0.64 | GRM5 (0.51) | — | |
| SCHEMBL18975875 | 0.64 | DRD3 (0.35) | DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107176955-A | A kind of Ba Rui replaces the preparation method of Buddhist nun | 南京优科制药有限公司 | 2017-09-19 | — | — | CN | claimed |
| CN-107176955-B | A kind of Ba Rui replaces the preparation method of Buddhist nun | 南京优科制药有限公司 | 2019-04-09 | — | — | CN | disclosed |
| CN-108586465-A | A kind of Ba Rui replaces the preparation method of Buddhist nun | 江苏中邦制药有限公司 | 2018-09-28 | — | — | CN | disclosed |
| CN-108341820-A | JAK enzyme inhibitors and its preparation method and application | 上海长森药业有限公司 | 2018-07-31 | — | — | CN | disclosed |
| CN-108129482-A | A kind of Ba Rui replaces the preparation method of Buddhist nun | 江苏中邦制药有限公司 | 2018-06-08 | — | — | CN | disclosed |
| CN-107698569-A | Connection pyrazole derivatives as JAK inhibitor | 因赛特公司 | 2018-02-16 | — | — | CN | disclosed |
| CN-105189509-B | For preparing the method and intermediate of JAK inhibitor | 因赛特公司 | 2017-12-19 | — | — | CN | disclosed |
| CN-105452239-B | Bipyrazole derivatives as JAK inhibitors | 因赛特公司 | 2017-11-21 | — | — | CN | disclosed |
| CN-107176955-A | A kind of Ba Rui replaces the preparation method of Buddhist nun | 南京优科制药有限公司 | 2017-09-19 | — | — | CN | disclosed |
| CN-105189498-B | Geminally substituted cyanoethylpyrazolopyridinones as JANUS kinase inhibitors | 默沙东公司 | 2017-06-27 | — | — | CN | disclosed |