Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PTPRB | P23467 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12266017 | 0.87 | KDM4E (0.49) | KDM4EPOLBTSHRALDH1A1KMT2A | |
| SCHEMBL4040412 | 0.85 | KDM4E (0.54) | KDM4EPOLBTSHRALDH1A1KMT2A | |
| SCHEMBL28114670 | 0.82 | KDM4E (0.51) | KDM4EPOLBTSHRALDH1A1KMT2A | |
| SCHEMBL17667387 | 0.80 | KDM4E (0.57) | KDM4EPOLBTSHRALDH1A1KMT2A | |
| SCHEMBL17667388 | 0.80 | KDM4E (0.57) | KDM4EPOLBTSHRALDH1A1KMT2A | |
| SCHEMBL7936507 | 0.80 | KDM4E (0.57) | KDM4EPOLBTSHRALDH1A1KMT2A | |
| SCHEMBL1691485 | 0.78 | ALDH1A1 (0.52) | KDM4EPOLBTSHRALDH1A1KMT2A | |
| SCHEMBL7391806 | 0.78 | SMN1; SMN2 (0.50) | ALDH1A1KMT2AMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL1691754 | 0.78 | KDM4E (0.53) | KDM4EPOLBTSHRALDH1A1KMT2A | |
| SCHEMBL7937989 | 0.76 | KDM4E (0.53) | KDM4EPOLBTSHRALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107188866-A | A kind of synthetic method of the ketone compounds of polysubstituted thiazole 4 | 湖北科技学院 | 2017-09-22 | — | — | CN | claimed |
| CN-107176925-A | A kind of synthetic method of the cyclohexadione compounds of polysubstituted imidazoline 2,4 | 湖北科技学院 | 2017-09-19 | — | — | CN | claimed |
| CN-106966990-A | A kind of synthetic method of the polysubstituted ketone compounds of 2 thiocarbamoyl imidazole quinoline 4 | 湖北科技学院 | 2017-07-21 | — | — | CN | claimed |