Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6053601 | 0.90 | TLR4 (0.52) | TLR4TSHRKDM4EPTK2BNPC1 | |
| SCHEMBL28159669 | 0.88 | TLR4 (0.46) | TLR4TSHRKDM4EPTK2BSMN1; SMN2 | |
| SCHEMBL871875 | 0.84 | TLR4 (0.69) | TLR4MEN1KMT2ATSHRLMNA | |
| SCHEMBL28159696 | 0.81 | TLR4 (0.48) | TLR4MEN1KMT2ATSHRLMNA | |
| SCHEMBL28159329 | 0.81 | TLR4 (0.55) | TLR4MEN1KMT2AMAPTRAB9A | |
| SCHEMBL27573690 | 0.81 | TLR4 (0.52) | TLR4MEN1KMT2ATSHRLMNA | |
| SCHEMBL6053336 | 0.79 | TLR4 (0.61) | TLR4MEN1KMT2ACXCR2MAPT | |
| SCHEMBL722368 | 0.79 | TLR4 (0.73) | TLR4MEN1KMT2ALMNAMAPT | |
| SCHEMBL3690868 | 0.79 | TLR4 (0.73) | TLR4MEN1KMT2ALMNAMAPT | |
| SCHEMBL872269 | 0.79 | TLR4 (0.73) | TLR4MEN1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102821763-B | Compound for inhibiting peripheral nerve disorder induced by anticancer agent | 武田药品工业株式会社 | 2017-09-22 | — | — | CN | disclosed |