Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 7/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28159281 | 0.88 | TLR4 (0.48) | TLR4TSHRKDM4EPTK2BSMN1; SMN2 | |
| SCHEMBL6053601 | 0.87 | TLR4 (0.52) | TLR4TSHRKDM4EPTK2BSMN1; SMN2 | |
| SCHEMBL27985969 | 0.85 | TLR4 (0.47) | TLR4L3MBTL1PDE4APDE4BPDE4C | |
| SCHEMBL27573674 | 0.83 | TLR4 (0.48) | TLR4TSHRSMN1; SMN2 | |
| SCHEMBL27883083 | 0.82 | TLR4 (0.41) | TLR4KDM4ESMN1; SMN2 | |
| SCHEMBL871684 | 0.82 | TLR4 (0.68) | TLR4CNR1L3MBTL1TSHRKDM4E | |
| SCHEMBL27573716 | 0.82 | TLR4 (0.48) | TLR4CNR1TSHRSMN1; SMN2 | |
| SCHEMBL27985646 | 0.81 | TLR4 (0.39) | TLR4 | |
| SCHEMBL28159329 | 0.80 | TLR4 (0.55) | TLR4ATML3MBTL1 | |
| SCHEMBL722368 | 0.78 | TLR4 (0.73) | TLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102821763-B | Compound for inhibiting peripheral nerve disorder induced by anticancer agent | 武田药品工业株式会社 | 2017-09-22 | — | — | CN | disclosed |