Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.43 |
| ▸ | ASPH | Q12797 | 2/20 | 0.43 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30968741 | 1.00 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNAKDM4EASPHKDM8 | |
| SCHEMBL28263946 | 0.88 | CYP1A2 (0.42) | SMN1; SMN2LMNAKDM4EASPHKDM8 | |
| SCHEMBL27976863 | 0.88 | KDM4E (0.44) | SMN1; SMN2LMNAKDM4EASPHKDM8 | |
| SCHEMBL24342426 | 0.82 | MAPT (0.37) | SMN1; SMN2LMNAKDM4EASPHKDM8 | |
| SCHEMBL312811 | 0.81 | TSHR (0.43) | LMNAKDM4EMAPTTSHRPOLB | |
| SCHEMBL21819468 | 0.81 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNAKDM4EASPHKDM8 | |
| SCHEMBL29543556 | 0.81 | MAPT (0.43) | LMNAKDM4EMAPTTSHRALDH1A1 | |
| SCHEMBL31032837 | 0.81 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNAKDM4EASPHKDM8 | |
| SCHEMBL362125 | 0.81 | ALDH1A1 (0.44) | SMN1; SMN2LMNAKDM4EMAPTTSHR | |
| SCHEMBL26910317 | 0.81 | MAPT (0.43) | LMNAKDM4EMAPTTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111808102-B | 3-methoxy-6, 7-dihydro-5H-pyrrolo [3,4-b ] pyridine hydrochloride and synthetic method thereof | 南通大学 | 2021-12-31 | — | — | CN | claimed |
| CN-111808102-A | 3-methoxy-6, 7-dihydro-5H-pyrrolo [3,4-b ] pyridine hydrochloride and synthetic method thereof | 南通大学 | 2020-10-23 | — | — | CN | claimed |
| CN-109467531-A | A kind of preparation method of substituted pyridines dicarboxylic acid derivatives | 沈阳科创化学品有限公司 | 2019-03-15 | — | — | CN | claimed |
| CN-106967213-A | Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance | 厦门赛诺邦格生物科技股份有限公司 | 2017-07-21 | — | — | CN | claimed |
| CN-111808102-B | 3-methoxy-6, 7-dihydro-5H-pyrrolo [3,4-b ] pyridine hydrochloride and synthetic method thereof | 南通大学 | 2021-12-31 | — | — | CN | disclosed |
| CN-111808102-B | 3-methoxy-6, 7-dihydro-5H-pyrrolo [3,4-b ] pyridine hydrochloride and synthetic method thereof | 南通大学 | 2021-12-31 | — | — | CN | disclosed |
| CN-111808102-A | 3-methoxy-6, 7-dihydro-5H-pyrrolo [3,4-b ] pyridine hydrochloride and synthetic method thereof | 南通大学 | 2020-10-23 | — | — | CN | disclosed |
| CN-111808102-A | 3-methoxy-6, 7-dihydro-5H-pyrrolo [3,4-b ] pyridine hydrochloride and synthetic method thereof | 南通大学 | 2020-10-23 | — | — | CN | disclosed |
| CN-106967213-B | Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance | 厦门赛诺邦格生物科技股份有限公司 | 2019-11-05 | — | — | CN | disclosed |
| CN-109666166-A | A kind of energy-absorbing method based on dynamic crosslinking polymer | 翁秋梅 | 2019-04-23 | — | — | CN | disclosed |
| CN-109666160-A | A kind of dynamic aggregation object with hybrid cross-linked network | 翁秋梅 | 2019-04-23 | — | — | CN | disclosed |
| CN-109467531-A | A kind of preparation method of substituted pyridines dicarboxylic acid derivatives | 沈阳科创化学品有限公司 | 2019-03-15 | — | — | CN | disclosed |
| CN-109467531-A | A kind of preparation method of substituted pyridines dicarboxylic acid derivatives | 沈阳科创化学品有限公司 | 2019-03-15 | — | — | CN | disclosed |
| CN-109096294-A | The preparation method of pyridine compounds | 周银平 | 2018-12-28 | — | — | CN | disclosed |
| CN-107698748-A | A kind of dynamic aggregation thing of hybrid cross-linked network and its application | 翁秋梅 | 2018-02-16 | — | — | CN | disclosed |
| CN-107235895-A | The method for preparing the dicarboxylic acid derivatives of 5 methoxypicoline 2,3 of substitution | 巴斯夫欧洲公司 | 2017-10-10 | — | — | CN | disclosed |
| CN-102245575-B | Process for preparing substituted 5-methoxymethylpyridine-2, 3-dicarboxylic acid derivatives | 巴斯夫欧洲公司 | 2017-07-28 | — | — | CN | disclosed |
| CN-106967213-A | Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance | 厦门赛诺邦格生物科技股份有限公司 | 2017-07-21 | — | — | CN | disclosed |