Methacrylic Acid

Methacrylic Acid

SCHEMBL28161998

C=C(C)C(=O)O.O=C(O)CCl.[Zn]

nearest known ligand 0.56

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Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.56
TDP1 Q9NUW8 2/20 0.45
HSD17B10 Q99714 2/20 0.45
ALDH1A1 P00352 2/20 0.33
FFAR3 O14843 2/20 0.33
LMNA P02545 1/20 0.33
SLC15A2 Q16348 1/20 0.33
HMGCR P04035 1/20 0.32
CHRM1 P11229 1/20 0.32
TBXA2R P21731 1/20 0.32
ADRA1A P35348 1/20 0.32
LCK P06239 1/20 0.32
FYN P06241 1/20 0.32
TGFBR1 P36897 1/20 0.31
ALOX15 P16050 1/20 0.31
TET2 Q6N021 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL8427253 0.97 TSHR (0.59) TSHRTDP1HSD17B10ALDH1A1FFAR3
Methacrylic Acid SCHEMBL27504847 0.94 TSHR (0.56) TSHRTDP1HSD17B10ALDH1A1FFAR3
Methacrylic Acid SCHEMBL27477526 0.94 TSHR (0.56) TSHRTDP1HSD17B10ALDH1A1FFAR3
Methacrylic Acid SCHEMBL10358418 0.94 TSHR (0.56) TSHRTDP1HSD17B10ALDH1A1FFAR3
Methacrylic Acid SCHEMBL10358453 0.94 TSHR (0.56) TSHRTDP1HSD17B10ALDH1A1FFAR3
Methacrylic Acid SCHEMBL28096441 0.85
Methacrylic Acid SCHEMBL28916683 0.82 TDP1 (0.42) TSHRTDP1HSD17B10ALDH1A1FFAR3
Methacrylic Acid SCHEMBL9352554 0.82 TDP1 (0.50) TSHRTDP1HSD17B10ALDH1A1FFAR3
Methacrylic Acid SCHEMBL48504 0.82
Methacrylic Acid SCHEMBL3224812 0.82 TDP1 (0.50) TSHRTDP1HSD17B10ALDH1A1FFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106905802-A Antifouling paint compositions and the coated article with its film 关西涂料株式会社 2017-06-30 CN disclosed