Methacrylic Acid

Methacrylic Acid

SCHEMBL8427253

C=C(C)C(=O)O.O=C(O)CCl

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.59
TDP1 Q9NUW8 2/20 0.47
HSD17B10 Q99714 2/20 0.47
FFAR3 O14843 3/20 0.35
ALDH1A1 P00352 2/20 0.35
LMNA P02545 1/20 0.35
SLC15A2 Q16348 1/20 0.35
ADRA1A P35348 2/20 0.33
HMGCR P04035 1/20 0.33
CHRM1 P11229 1/20 0.33
TBXA2R P21731 1/20 0.33
LCK P06239 1/20 0.33
FYN P06241 1/20 0.33
TGFBR1 P36897 1/20 0.32
ALOX15 P16050 1/20 0.32
TET2 Q6N021 1/20 0.31
HDAC3 O15379 1/20 0.30
HDAC1 Q13547 1/20 0.30
HDAC2 Q92769 1/20 0.30
HDAC8 Q9BY41 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL10358418 0.97 TSHR (0.56) TSHRTDP1HSD17B10FFAR3ALDH1A1
Methacrylic Acid SCHEMBL27504847 0.97 TSHR (0.56) TSHRTDP1HSD17B10FFAR3ALDH1A1
Methacrylic Acid SCHEMBL28161998 0.97 TSHR (0.56) TSHRTDP1HSD17B10FFAR3ALDH1A1
Methacrylic Acid SCHEMBL27477526 0.97 TSHR (0.56) TSHRTDP1HSD17B10FFAR3ALDH1A1
Methacrylic Acid SCHEMBL10358453 0.97 TSHR (0.56) TSHRTDP1HSD17B10FFAR3ALDH1A1
Methacrylic Acid SCHEMBL28096441 0.88
Methacrylic Acid SCHEMBL28916683 0.85 TDP1 (0.42) TSHRTDP1HSD17B10FFAR3ALDH1A1
Methacrylic Acid SCHEMBL16506807 0.82 TDP1 (0.40) TSHRTDP1HSD17B10FFAR3ALDH1A1
Methacrylic Acid SCHEMBL1623920 0.81 TDP1 (0.41) TSHRTDP1HSD17B10FFAR3ALDH1A1
Chloroacetic Acid SCHEMBL444733 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5891935-A Process for preparing polymeric binders and their use for antifouling paint systems WITCO GMBH (DE) 1999-04-06 US disclosed