Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | AOC1 | P19801 | 2/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28214123 | 0.84 | GAA (0.42) | ALDH1A1KDM4EMAPTMEN1KDM6B | |
| SCHEMBL9207139 | 0.81 | CA12 (0.37) | ALDH1A1KDM4CAOC1AOC3CA12 | |
| SCHEMBL14361044 | 0.76 | PTGS1 (0.37) | KDM4CTDP1L3MBTL1CA12CA1 | |
| SCHEMBL19943717 | 0.74 | AOC1 (0.35) | ALDH1A1KDM4EMAPTMEN1KDM6B | |
| SCHEMBL9330010 | 0.74 | — | — | |
| SCHEMBL30074192 | 0.72 | — | — | |
| SCHEMBL2046959 | 0.72 | — | — | |
| SCHEMBL25297060 | 0.72 | KDM4C (0.34) | ALDH1A1KDM6BKDM4DKDM4CAOC1 | |
| SCHEMBL18857496 | 0.72 | CA12 (0.46) | ALDH1A1KDM4EMAPTMEN1KDM6B | |
| SCHEMBL28866140 | 0.72 | PTGS1 (0.41) | MAPTKDM4CTDP1AOC1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117756718-A | Preparation method of high-yield 3-amino-4-formamido pyrazole hemisulfate | 宜兴市星宇药业有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-117756718-A | Preparation method of high-yield 3-amino-4-formamido pyrazole hemisulfate | 宜兴市星宇药业有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-115353508-A | 5-pyridine-1H-indazole compound, pharmaceutical composition and application | 中国药科大学 | 2022-11-18 | — | — | CN | disclosed |
| CN-110167926-A | POLY-ADP RIBOSE POLYMERASE (PARP) INHIBITORS | 米托布里奇公司 | 2019-08-23 | — | — | CN | disclosed |
| CN-107205391-A | Histone demethylase inhibitors | 赛尔基因昆蒂赛尔研究公司 | 2017-09-26 | — | — | CN | disclosed |
| CN-107001358-A | Adjust the new pyridine hepyramine compound of istone lysine demethylase (KDM) catalytic activity | 东亚ST株式会社 | 2017-08-01 | — | — | CN | disclosed |