SCHEMBL2816420

SCHEMBL2816420

C=C(C)C(=O)C(C=O)c1ccc(O)c(-n2nc3ccc(Cl)cc3n2)c1

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.36
LMNA P02545 1/20 0.36
RAB9A P51151 1/20 0.36
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
ERN1 O75460 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25409014 0.79 NPC1 (0.36) NPC1LMNARAB9AMEN1KMT2A
SCHEMBL16499613 0.78 MEN1 (0.31) MEN1KMT2A
SCHEMBL7032725 0.77 NPC1 (0.46) NPC1LMNARAB9AMEN1KMT2A
SCHEMBL23214331 0.77 NPC1 (0.34) NPC1LMNARAB9AMEN1KMT2A
SCHEMBL25409485 0.75 NPC1 (0.36) NPC1LMNARAB9AMEN1KMT2A
SCHEMBL508724 0.74 RXFP1 (0.42) NPC1LMNARAB9AMEN1KMT2A
SCHEMBL5178883 0.74 NPC1 (0.39) NPC1LMNARAB9AMEN1KMT2A
SCHEMBL29400067 0.74 RXFP1 (0.42) NPC1LMNARAB9AMEN1KMT2A
SCHEMBL28061360 0.74 NPC1 (0.43) NPC1LMNARAB9AMEN1KMT2A
SCHEMBL11418479 0.74 NPC1 (0.51) NPC1LMNARAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100243030-A1 SUBSTRATE AND POSITIONING METHOD THEREOF, PHOTOELECTRIC CONVERSION DEVICE AND MANUFACTURING METHOD AND APPARATUS THEREFOR, AND SOLAR CELL FUJIFILM CORPORATION (JP) 2010-09-30 US disclosed
EP-1067223-B1 Highly light-resistant fibers, and process for producing the fibers NIPPON CATALYTIC CHEM IND (JP) 2005-04-06 EP disclosed
US-6312802-B1 ADDITION POLYMERS OF 2,2,6,6-TETRAMETHYL-4-PIPERAZINYL ACRYLATES OR ACRYLAMIDES; ADDITION POLYMERS OF (BENZOTRIAZOL-2'-YL)HYDROXYPHENYL ACRYLATES NIPPON SHOKUBAI CO., LTD. (JP) 2001-11-06 US disclosed