Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.64 |
| ▸ | GSK3B | P49841 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | NAT1 | P18440 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Rhodanine SCHEMBL94126 | 0.80 | — | — | |
| Rhodanine SCHEMBL2229918 | 0.80 | GSK3A (1.00) | GSK3AGSK3BHPGDEPHX2USP2 | |
| Catechol SCHEMBL3758856 | 0.80 | GSK3A (0.56) | GSK3AGSK3BHPGDEPHX2USP2 | |
| Rhodanine SCHEMBL55625 | 0.80 | — | — | |
| Catechol SCHEMBL2781528 | 0.80 | GSK3A (0.67) | GSK3AGSK3BHPGDEPHX2USP2 | |
| Benzaldehyde SCHEMBL9354550 | 0.79 | GSK3A (0.60) | GSK3AGSK3BHPGDUSP2ALDH1A1 | |
| Rhodanine SCHEMBL5919491 | 0.78 | — | — | |
| Rhodanine SCHEMBL8017015 | 0.78 | — | — | |
| Rhodanine SCHEMBL10704409 | 0.78 | — | — | |
| Rhodanine SCHEMBL2403229 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104387378-B | 4 Thiazolidinones and its application | 沈阳药科大学 | 2017-08-25 | — | — | CN | disclosed |