Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28164297 | 0.86 | ADORA3 (0.34) | HTR2CHTR2B | |
| SCHEMBL28164815 | 0.76 | TTK (0.33) | HTR2CHTR2B | |
| SCHEMBL28292528 | 0.76 | POLB (0.38) | POLBELANE | |
| SCHEMBL28292558 | 0.74 | ALOX5AP (0.38) | HTR2CHTR2BGPR84 | |
| SCHEMBL19362470 | 0.69 | ADORA2A (0.39) | — | |
| SCHEMBL28164295 | 0.67 | TAAR1 (0.49) | POLBHTR2CHTR2BGPR84 | |
| SCHEMBL19619651 | 0.66 | MAPK1 (0.35) | — | |
| SCHEMBL19930116 | 0.65 | PIP4K2C (0.41) | — | |
| SCHEMBL28164810 | 0.63 | IDO1 (0.43) | — | |
| SCHEMBL2611063 | 0.63 | APP (0.35) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074866-B | Pyrimido-pyrrole compound, preparation method thereof, medicinal composition and application thereof | 厦门大学 | 2019-06-07 | — | — | CN | claimed |
| CN-107074866-A | Pyrimido-pyrrole compound, preparation method thereof, medicinal composition and application thereof | 厦门大学 | 2017-08-18 | — | — | CN | claimed |