SCHEMBL28165656

SCHEMBL28165656

CCCCO[Si](C)(OCCCC)C(O)CC

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
ALDH1A1 P00352 1/20 0.32
ADRB2 P07550 1/20 0.32
ADRB1 P08588 1/20 0.32
ADRB3 P13945 1/20 0.32
USP2 O75604 1/20 0.31
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28125247 0.86 HSD17B10 (0.34) TSHR
SCHEMBL27627167 0.77 TSHR (0.33) TSHR
SCHEMBL28767138 0.76 ADRB2 (0.33) TSHRADRB2ADRB1ADRB3
SCHEMBL28444998 0.75 ADRB2 (0.36) TSHRALDH1A1ADRB2ADRB1ADRB3
SCHEMBL8512659 0.75 ADRB2 (0.36) TSHRALDH1A1ADRB2ADRB1ADRB3
Phosphine SCHEMBL28031046 0.75 TSHR (0.32) TSHR
Ammonia Solution, Strong SCHEMBL28099820 0.75 TSHR (0.32) TSHR
Water SCHEMBL28128864 0.75 TSHR (0.32) TSHR
SCHEMBL27922597 0.74 CYP3A4 (0.33) ALDH1A1ADRB2ADRB1ADRB3ATM
SCHEMBL15023899 0.72 ADRB2 (0.31) ADRB2ADRB1ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109642009-A SILANE-FUNCTIONAL POLYMERIC POLYURETHANES 科思创德国股份有限公司 2019-04-16 CN disclosed
CN-108027565-A Photosensitive polymer combination, cured film, the manufacture method of touch panel and touch panel 东丽株式会社 2018-05-11 CN disclosed
CN-107960095-A Coating composition and optical member 日产化学工业株式会社 2018-04-24 CN disclosed
CN-107075302-A The film formation composition of the silicon containing crosslinking reactivity 日产化学工业株式会社 2017-08-18 CN disclosed