Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 3/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | PLG | P00747 | 1/20 | 0.31 |
| ▸ | QDPR | P09417 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1545610 | 0.90 | HRH4 (0.33) | SLC18A3SIGMAR1HTR3A | |
| SCHEMBL19348393 | 0.84 | — | — | |
| SCHEMBL15924379 | 0.78 | — | — | |
| SCHEMBL2121563 | 0.73 | — | — | |
| SCHEMBL6788944 | 0.73 | — | — | |
| SCHEMBL11381299 | 0.71 | HRH4 (0.32) | — | |
| SCHEMBL27449730 | 0.70 | — | — | |
| SCHEMBL27468917 | 0.70 | NISCH (0.30) | — | |
| SCHEMBL828613 | 0.70 | HRH4 (0.34) | SLC18A3SIGMAR1HTR3AMAPT | |
| SCHEMBL27450276 | 0.68 | NISCH (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074804-A | Carbazole derivates | 百时美施贵宝公司 | 2017-08-18 | — | — | CN | claimed |
| WO-2023016521-A1 | SUBSTITUTED TRIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | 上海赛默罗生物科技有限公司 | 2023-02-16 | — | — | WO | disclosed |
| CN-107074804-A | Carbazole derivates | 百时美施贵宝公司 | 2017-08-18 | — | — | CN | disclosed |