Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methoxymethane SCHEMBL3899156 | 0.93 | HTR2C (0.34) | HRH4HTR3A | |
| SCHEMBL1586586 | 0.92 | KDM1A (0.31) | KDM1AMAPT | |
| SCHEMBL6788944 | 0.87 | — | — | |
| Quinoxaline SCHEMBL7485007 | 0.83 | MEN1 (0.35) | SLC18A3SIGMAR1 | |
| SCHEMBL1650443 | 0.82 | HRH4 (0.37) | HRH4HTR3ASLC18A3SIGMAR1MAPT | |
| SCHEMBL571897 | 0.81 | — | — | |
| SCHEMBL14741159 | 0.81 | — | — | |
| SCHEMBL32689488 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL9391692 | 0.79 | KDM1A (0.31) | KDM1A | |
| SCHEMBL27752202 | 0.79 | KDM1A (0.44) | HRH4HTR3ASLC18A3SIGMAR1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 853 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3227270-B1 | HETEROCYCLIC DERIVATIVES AND USE THEREOF | C&C RES LAB (KR) | 2024-11-13 | — | — | EP | claimed |
| CN-112457247-A | Synthesis method of dextromethorphan chiral intermediate | 江苏宝众宝达药业有限公司 | 2021-03-09 | — | — | CN | claimed |
| CN-104761496-B | Synthesis method of dextromethorphan intermediate | 华东理工大学 | 2017-05-24 | — | — | CN | claimed |
| CN-105524971-A | Novel method for resolving 1-(4-methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline through enzyme catalysis | TIANJIN INST IND BIOTECHNOLOGY | 2016-04-27 | — | — | CN | claimed |
| US-9139552-B2 | Indeno-fused naphthopyrans having ethylenically unsaturated groups | TRANSITIONS OPTICAL, INC. (US) | 2015-09-22 | — | — | US | claimed |
| CN-104761494-A | Preparation method of (S) or (R)-1-(4-methoxy benzyl)-1,2,3,4,5,6,7,8-octahydro isoquinoline | SHANGHAI INST PHARM INDUSTRY | 2015-07-08 | — | — | CN | claimed |
| CN-104761496-A | Synthesis method of dextromethorphan intermediate | UNIV EAST CHINA SCIENCE & TECH | 2015-07-08 | — | — | CN | claimed |
| CN-103319406-A | Resolution of 1-(4-methoxybenzyl)-octahydro-isoquinoline | DIVIS LAB LTD | 2013-09-25 | — | — | CN | claimed |
| CN-103288731-A | Preparation method of dimemorfan phosphate intermediate | SICHUAN BIOKIN PHARMACEUTICAL CO LTD | 2013-09-11 | — | — | CN | claimed |
| CN-103265489-A | Preparation method of ent-(14S)-3-methoxyl-17-morphinan | Suzhou lixin pharmaceutical co ltd | 2013-08-28 | — | — | CN | claimed |
| US-7229986-B2 | Melanin-concentrating hormone antagonist | TAKEDA PHARMACEUTICAL COMPANY LTD. (JP) | 2007-06-12 | — | — | US | claimed |
| CN-1639127-A | Process for asymmetric hydrogenation of hexahydroquinoline salts | DSM IP ASSETS BV (NL) | 2005-07-13 | — | — | CN | claimed |
| CN-1139576-C | Process for manufacture of optically active (R)-or (S)-1-(4-methoxy-benzyl)-8-octahydro-isoquinoline adducts of the general formula | - | 2004-02-25 | — | — | CN | claimed |
| US-6337330-B1 | Antitussives | TORAY INDUSTRIES, INC. (JP) | 2002-01-08 | — | — | US | claimed |
| EP-1150565-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION bioscience AG (DE) | 2001-11-07 | — | — | EP | claimed |
| WO-2000045635-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2000-08-10 | — | — | WO | claimed |
| EP-0998928-A1 | ANTITUSSIVES | TORAY INDUSTRIES, INC. (JP) | 2000-05-10 | — | — | EP | claimed |
| CN-1186073-A | Process for manufacture of optically active (R)-or (S)-1-(4-methoxy-benzyl)-8-octahydro-isoquinoline adducts of the general formula | HOFFMANN LA ROCHE (CH) | 1998-07-01 | — | — | CN | claimed |
| EP-0023569-B1 | DERIVATIVES OF CARBOXYLIC ACIDS, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1983-06-22 | — | — | EP | claimed |
| EP-0023569-A1 | Derivatives of carboxylic acids, their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1981-02-11 | — | — | EP | claimed |