Glutamic Acid

Glutamic Acid

SCHEMBL28166196

N.N[C@@H](CCC(=O)O)C(=O)O.[Fe]

nearest known ligand 0.90

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM8 O00222 2/20 0.90
GRM6 O15303 2/20 0.90
GRM7 Q14831 2/20 0.90
GRM4 Q14833 2/20 0.90
GSR P00390 2/20 0.90
GRIN2D O15399 1/20 0.90
GRIN3B O60391 1/20 0.90
CYP1A2 P05177 1/20 0.90
GRIK1 P39086 1/20 0.90
GRM5 P41594 1/20 0.90
GRIA1 P42261 1/20 0.90
GRIA2 P42262 1/20 0.90
GRIA3 P42263 1/20 0.90
SLC1A3 P43003 1/20 0.90
SLC1A2 P43004 1/20 0.90
SLC1A1 P43005 1/20 0.90
GRIA4 P48058 1/20 0.90
GRIN1 Q05586 1/20 0.90
GRIN2A Q12879 1/20 0.90
GRIK2 Q13002 1/20 0.90

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
D-Glutamate SCHEMBL28166198 1.00 GRM8 (0.90) GRM8GRM6GRM7GRM4GSR
Glutamic Acid SCHEMBL648218 0.97 GRM8 (0.95) GRM8GRM6GRM7GRM4GSR
Glutamic Acid SCHEMBL671942 0.97 GRM8 (0.95) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL21072467 0.97 GRM8 (0.95) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL648217 0.97 GRM8 (0.95) GRM8GRM6GRM7GRM4GSR
Glutamic Acid SCHEMBL3884849 0.97 GRM8 (0.95) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL671944 0.97 GRM8 (0.95) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL978651 0.97 GRM8 (0.95) GRM8GRM6GRM7GRM4GSR
Glutamic Acid SCHEMBL30525806 0.95 GRM8 (0.90) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL2163608 0.95 GRM8 (0.90) GRM8GRM6GRM7GRM4GSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103747784-B The prophylactic and/or therapeutic agent of septicemia 思佰益药业股份有限公司 2018-01-30 CN disclosed
CN-104487067-B Prophylactic/therapeutic agent for influenza virus infection 思佰益药业股份有限公司 2017-09-01 CN disclosed