D-Glutamate

D-Glutamate

SCHEMBL648217

N.NC(CCC(=O)O)C(=O)O

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM8 O00222 2/20 0.95
GRM6 O15303 2/20 0.95
GRM7 Q14831 2/20 0.95
GRM4 Q14833 2/20 0.95
GSR P00390 2/20 0.95
GRIN2D O15399 1/20 0.95
GRIN3B O60391 1/20 0.95
CYP1A2 P05177 1/20 0.95
GRIK1 P39086 1/20 0.95
GRM5 P41594 1/20 0.95
GRIA1 P42261 1/20 0.95
GRIA2 P42262 1/20 0.95
GRIA3 P42263 1/20 0.95
SLC1A3 P43003 1/20 0.95
SLC1A2 P43004 1/20 0.95
SLC1A1 P43005 1/20 0.95
GRIA4 P48058 1/20 0.95
GRIN1 Q05586 1/20 0.95
GRIN2A Q12879 1/20 0.95
GRIK2 Q13002 1/20 0.95

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
D-Glutamate SCHEMBL978651 1.00 GRM8 (0.95) GRM8GRM6GRM7GRM4GSR
Glutamic Acid SCHEMBL648218 1.00 GRM8 (0.95) GRM8GRM6GRM7GRM4GSR
Glutamic Acid SCHEMBL671942 1.00 GRM8 (0.95) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL671944 1.00 GRM8 (0.95) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL28166198 0.97 GRM8 (0.90) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL27549484 0.97 GRM8 (0.90) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL28006261 0.97 GRM8 (0.90) GRM8GRM6GRM7GRM4GSR
Glutamic Acid SCHEMBL30525806 0.97 GRM8 (0.90) GRM8GRM6GRM7GRM4GSR
Glutamic Acid SCHEMBL28091015 0.97 GRM8 (0.90) GRM8GRM6GRM7GRM4GSR
Glutamic Acid SCHEMBL28166196 0.97 GRM8 (0.90) GRM8GRM6GRM7GRM4GSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118976052-A Preparation method and application of polyphenol extract of fresh flavedo of flavedo 江苏海洋大学 2024-11-19 CN claimed
CN-118874229-A Separation membrane for delaying physical aging and preparation method and application thereof 天津大学 2024-11-01 CN claimed
CN-118638826-A Application of surfactant or nano-disc in synthesizing membrane protein in cell-free synthesis system 清华大学 2024-09-13 CN claimed
CN-118638764-A Method for producing ACE2 using cell-free protein expression system and use of ACE2 清华大学 2024-09-13 CN claimed
CN-118165851-A Additives for cell-free reaction systems, compositions and uses thereof 清华大学 2024-06-11 CN claimed
CN-117942408-A Inorganic nano-enzyme for catalyzing glutamic acid to convert ammonia, preparation method and application thereof in bone cancer pain treatment medicine 复旦大学 2024-04-30 CN claimed
CN-117732092-A High-efficiency low-energy-consumption amino acid evaporative crystallization equipment and process 山东祥瑞药业有限公司 2024-03-22 CN claimed
CN-116832873-B Complex iron catalyst for removing hydrogen sulfide in industrial gas and preparation method thereof 西北大学 2024-02-27 CN claimed
CN-115531335-B Oselta phosphate Wei Kou disintegrating tablet and preparation method thereof 合肥医工医药股份有限公司 2024-01-30 CN claimed
CN-117310064-A Method for detecting 21 free amino acids in tea leaves 西北农林科技大学 2023-12-29 CN claimed
CN-108047163-A A kind of preparation method of Repaglinide 广州小桔生物科技有限公司 2018-05-18 CN claimed
CN-105916577-B The high concentration silver solution prepared for epoxyethane catalyst 科学设计有限公司 2018-03-30 CN claimed
CN-107473908-A A kind of rice plantation organic fertilizer 安徽联邦农业科技有限公司 2017-12-15 CN claimed
CN-107337611-A A kind of method that glutami acid fermentation liquor prepares sodium glutamate 成都连接流体分离科技有限公司 2017-11-10 CN claimed
CN-107197859-A A kind of fresh-keeping liquid for fresh flower and preparation method thereof 合肥申沃园艺有限公司 2017-09-26 CN claimed
CN-105916577-A High-concentration silver solutions for ethylene oxide catalyst preparation 科学设计有限公司 2016-08-31 CN claimed
EP-2661493-B1 PLASMINOGEN AND PLASMIN VARIANTS THROMBOGENICS NV (BE) 2016-03-30 EP claimed
CN-103798228-B A kind of flower antistaling agent containing polyglutamic acid or its salt SHANDONG FREDA BIOTECHNOLOGY CO., LTD. (CN) 2016-03-09 CN claimed
CN-103798228-A Flower fresh-keeping agent containing polyglutamic acid or salt of polyglutamic acid SHANDONG FREDA BIOTECHNOLOGY CO LTD 2014-05-21 CN claimed
CN-1041159-A Peptide compounds HAFSLUND NYCOMED BIOREG (NO) 1990-04-11 CN claimed