Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 2/20 | 0.38 |
| ▸ | CCR8 | P51685 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31298631 | 1.00 | KDM4E (0.42) | KDM4EMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8324162 | 0.78 | CCR1 (0.43) | KDM4EMEN1CYP1A2CYP3A4CYP2D6 | |
| Ammonia Solution, Strong SCHEMBL28471192 | 0.77 | CCR1 (0.42) | KDM4EMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29468208 | 0.77 | AHR (0.47) | KDM4EMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL19233651 | 0.77 | CDC7 (0.46) | KDM4EMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL16620535 | 0.77 | AHR (0.41) | KDM4EMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL31298639 | 0.77 | KDM4E (0.42) | KDM4EMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL19841330 | 0.74 | RORC (0.41) | KDM4EMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL12724778 | 0.74 | KDM4E (0.57) | KDM4EMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10218716 | 0.74 | KDM4E (0.40) | KDM4EMEN1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104892502-B | It is used as the aryl-pyridine of aldosterone synthase inhibitors | 诺华股份有限公司 | 2017-08-04 | — | — | CN | disclosed |