Fludioxonil

Fludioxonil

SCHEMBL28166226

N#Cc1c[nH]cc1-c1cccc2c1OC(F)(F)O2.O=C1NC(=O)c2ccccc21

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 0.35
FFAR4 Q5NUL3 1/20 0.32
CASP3 P42574 1/20 0.32
CASP2 P42575 1/20 0.32
CASP7 P55210 1/20 0.32
CASP6 P55212 1/20 0.32
CASP8 Q14790 1/20 0.32
KCNH2 Q12809 1/20 0.30
MCL1 Q07820 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fludioxonil SCHEMBL3948929 0.92 FFAR4 (0.34) FFAR4
Fludioxonil SCHEMBL29368170 0.92 FFAR4 (0.34) FFAR4
Fludioxonil SCHEMBL312648 0.90 FFAR4 (0.33) FFAR4
Fludioxonil SCHEMBL29038998 0.90 FFAR4 (0.33) FFAR4
Fludioxonil SCHEMBL5068204 0.90 FFAR4 (0.33) FFAR4KCNH2
Fludioxonil SCHEMBL28966267 0.87 FFAR4 (0.37) FFAR4KCNH2
Fludioxonil SCHEMBL28180074 0.86 FFAR4 (0.31) FFAR4
Fludioxonil SCHEMBL28290758 0.86 FFAR4 (0.35) FFAR4
Fludioxonil SCHEMBL28326370 0.84 FFAR4 (0.33) FFAR4KCNH2
Fludioxonil SCHEMBL27879773 0.83 FFAR4 (0.37) FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108883148-A The peptide and application thereof in allergic reaction exciton source 植物保健公司 2018-11-23 CN disclosed
CN-107041140-A Elicitor peptides with a disrupted hypersensitive response cassette and uses thereof 植物保健公司 2017-08-11 CN disclosed
CN-107002091-A Allergic reaction exciton peptide and application thereof 植物保健公司 2017-08-01 CN disclosed