Fludioxonil

Fludioxonil

SCHEMBL3948929

N#Cc1c[nH]cc1-c1cccc2c1OC(F)(F)O2.N#Cc1c[nH]cc1-c1cccc2c1OC(F)(F)O2

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 1/20 0.34
JAK2 O60674 1/20 0.32
JAK3 P52333 1/20 0.32
PTK2 Q05397 1/20 0.32
GPR3 P46089 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fludioxonil SCHEMBL29368170 1.00 FFAR4 (0.34) FFAR4JAK2JAK3PTK2GPR3
Fludioxonil SCHEMBL5068204 0.99 FFAR4 (0.33) FFAR4JAK2JAK3PTK2
Fludioxonil SCHEMBL312648 0.99 FFAR4 (0.33) FFAR4JAK2JAK3PTK2
Fludioxonil SCHEMBL29038998 0.99 FFAR4 (0.33) FFAR4JAK2JAK3PTK2
Fludioxonil SCHEMBL28180074 0.94 FFAR4 (0.31) FFAR4JAK2JAK3PTK2
Fludioxonil SCHEMBL28290758 0.94 FFAR4 (0.35) FFAR4JAK2JAK3PTK2
Fludioxonil SCHEMBL28966267 0.93 FFAR4 (0.37) FFAR4JAK2JAK3PTK2
Fludioxonil SCHEMBL28166226 0.92 GSK3B (0.35) FFAR4
Fludioxonil SCHEMBL5072145 0.91 CNR2 (0.33) FFAR4
Fludioxonil SCHEMBL28326370 0.89 FFAR4 (0.33) FFAR4JAK2JAK3PTK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012146936-A1 PYRROLNITRIN DERIVATIVES CXR BIOSCIENCES LIMITED (GB) 2012-11-01 WO disclosed
EP-2076130-A2 A METHOD FOR ENHANCING INTRINSIC PRODUCTIVITY OF A PLANT Syngeta Participations AG (CH) 2009-07-08 EP disclosed
WO-2008037489-A2 A METHOD FOR ENHANCING INTRINSIC PRODUCTIVITY OF A PLANT SYNGENTA PARTICIPATIONS AG (CH) 2008-04-03 WO disclosed
US-5843982-A Fungicidal compositions comprising metalaxyl and fludioxonil NOVARTIS FINANCE CORPORATION (US) 1998-12-01 US disclosed
WO-1997036471-A1 GELATIN-BASED COATINGS FOR PLANT SEEDS AND PROPAGULES MONSANTO COMPANY (US) 1997-10-09 WO disclosed