SCHEMBL28166338

SCHEMBL28166338

CCCCCCc1ccc(I)cc1CCCCCC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.50
TSHR P16473 2/20 0.50
TP53 P04637 2/20 0.50
CYP3A4 P08684 2/20 0.50
MEN1 O00255 1/20 0.50
ALOX5 P09917 1/20 0.50
MAPT P10636 1/20 0.50
ALOX15 P16050 1/20 0.50
HTT P42858 1/20 0.50
KMT2A Q03164 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
LIPG Q9Y5X9 1/20 0.43
PTGS2 P35354 3/20 0.38
ESR1 P03372 2/20 0.38
ADRA2A P08913 2/20 0.38
ADORA3 P0DMS8 2/20 0.38
TACR2 P21452 2/20 0.38
SLC6A2 P23975 2/20 0.38
SLC6A4 P31645 2/20 0.38
SLC6A3 Q01959 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25922202 0.92 TYR (0.47) TYRTSHRTP53CYP3A4MEN1
SCHEMBL5684607 0.86 TYR (0.53) TYRTSHRTP53CYP3A4MEN1
SCHEMBL3657714 0.86 ALOX5 (0.44) TYRTSHRTP53CYP3A4MEN1
SCHEMBL11572449 0.84 ALOX5 (0.45) TYRTSHRTP53CYP3A4MEN1
SCHEMBL11570168 0.84 ALOX5 (0.45) TYRTSHRTP53CYP3A4MEN1
SCHEMBL11571261 0.84 ALOX5 (0.45) TYRTSHRTP53CYP3A4MEN1
SCHEMBL11571145 0.84 TSHR (0.42) TYRTSHRTP53CYP3A4MEN1
SCHEMBL11587871 0.83 TYR (0.54) TYRTSHRTP53CYP3A4MEN1
SCHEMBL9850753 0.83 TYR (0.50) TYRTSHRTP53CYP3A4MEN1
SCHEMBL14220741 0.83 IDO1 (0.34) TYRTSHRTP53CYP3A4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107108861-B hole transport material 株式会社LG化学 2019-11-12 CN disclosed
CN-107108861-A Hole mobile material E.I.内穆尔杜邦公司 2017-08-29 CN disclosed