Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27965527 | 1.00 | MGAM (0.36) | MGAMGAASIMGAM2USP2 | |
| SCHEMBL5796636 | 0.74 | MGAM (0.48) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL28060046 | 0.71 | GAA (0.34) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL27842025 | 0.71 | MGAM (0.44) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL27281883 | 0.71 | MGAM (0.44) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL27752668 | 0.70 | GAA (0.36) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL28228142 | 0.69 | MGAM (0.43) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL1617620 | 0.69 | MGAM (0.43) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL28093614 | 0.69 | MGAM (0.43) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL9510650 | 0.69 | MGAM (0.39) | MGAMGAASIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103857681-B | It is used as the new big ring of factor XI, plasma thromboplastin antecedent A inhibitor | 百时美施贵宝公司 | 2017-07-14 | — | — | CN | disclosed |