Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SI | P14410 | 2/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5796636 | 0.81 | MGAM (0.48) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL1617620 | 0.76 | MGAM (0.43) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL16667687 | 0.74 | MGAM (0.50) | MGAMGAASIMGAM2 | |
| SCHEMBL11144532 | 0.72 | MGAM (0.48) | MGAMGAASIMGAM2 | |
| SCHEMBL9513 | 0.72 | TSHR (0.50) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL9510650 | 0.72 | MGAM (0.39) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL28901695 | 0.72 | MGAM (0.46) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL5134550 | 0.71 | TSHR (0.48) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL2221470 | 0.71 | TSHR (0.48) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL5702374 | 0.71 | TSHR (0.48) | MGAMGAASIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108707151-A | Pyrimido-pyridazinone compound and application thereof | 阿萨纳生物科技有限责任公司 | 2018-10-26 | — | — | CN | disclosed |
| CN-103974955-B | Pyrimido-pyridazinone compounds and uses thereof | 阿萨纳生物科技有限责任公司 | 2018-06-19 | — | — | CN | disclosed |