SCHEMBL28166709 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	GSK3B	P49841	7/20	0.61

▸	DYRK1A	Q13627	7/20	0.61

▸	ABL1	P00519	8/20	0.44

▸	WNT1	P04628	2/20	0.41

▸	SYK	P43405	1/20	0.40

▸	JAK2	O60674	1/20	0.39

▸	TYK2	P29597	1/20	0.39

▸	MAPKAPK2	P49137	1/20	0.38

▸	NOTUM	Q6P988	1/20	0.38

▸	MAPK1	P28482	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL4302469	0.84	GSK3B (0.61)	GSK3BDYRK1AABL1WNT1
SCHEMBL29650022	0.84	GSK3B (0.61)	GSK3BDYRK1AABL1WNT1
SCHEMBL28166698	0.83	GSK3B (0.60)	GSK3BDYRK1AABL1SYKNOTUM
SCHEMBL30636341	0.83	GSK3B (0.60)	GSK3BDYRK1AABL1SYKNOTUM
SCHEMBL17631721	0.83	DYRK1A (0.60)	GSK3BDYRK1AABL1WNT1MAPK1
SCHEMBL29710311	0.83	DYRK1A (0.60)	GSK3BDYRK1AABL1WNT1MAPK1
SCHEMBL29710317	0.83	DYRK1A (0.60)	GSK3BDYRK1AABL1WNT1MAPK1
SCHEMBL17631521	0.82	GSK3B (0.59)	GSK3BDYRK1AABL1WNT1
SCHEMBL17643975	0.81	DYRK1A (0.58)	GSK3BDYRK1AABL1WNT1
SCHEMBL29993248	0.81	DYRK1A (0.58)	GSK3BDYRK1AABL1WNT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-107001339-A	Novel compounds	特殊治疗有限公司	2017-08-01	—	—	CN	disclosed